Case report: Therapeutic drug monitoring and CYP2D6 phenoconversion in a protracted paroxetine intoxication

ObjectiveThe cytochrome P450 2D6 (CYP2D6) is an enzyme involved in the oxidative biotransformation of various widely used drugs, including paroxetine, a substrate and strong inhibitor of the enzyme. The aim is to report on a case of protracted intoxication with paroxetine after a single overdose in...

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Principais autores: Alena Damborská (Autor), Lenka Hanáková (Autor), Eva Pindurová (Autor), Kateřina Horská (Autor)
Formato: Livro
Publicado em: Frontiers Media S.A., 2024-09-01T00:00:00Z.
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