Case report: Therapeutic drug monitoring and CYP2D6 phenoconversion in a protracted paroxetine intoxication

• Κύριοι συγγραφείς: Alena Damborská (Συγγραφέας), Lenka Hanáková (Συγγραφέας), Eva Pindurová (Συγγραφέας), Kateřina Horská (Συγγραφέας)
• Μορφή: Βιβλίο
• Έκδοση: Frontiers Media S.A., 2024-09-01T00:00:00Z.
• Θέματα: article
• Διαθέσιμο Online: Connect to this object online.

ObjectiveThe cytochrome P450 2D6 (CYP2D6) is an enzyme involved in the oxidative biotransformation of various widely used drugs, including paroxetine, a substrate and strong inhibitor of the enzyme. The aim is to report on a case of protracted intoxication with paroxetine after a single overdose in...