Nucleoside Analog 2',3'-Isopropylidene-5-Iodouridine as Novel Efficient Inhibitor of HIV-1

• Hauptverfasser: Ksenia Glumakova (Verfasst von), Georgy Ivanov (Verfasst von), Valeria Vedernikova (Verfasst von), Lena Shyrokova (Verfasst von), Timofey Lebedev (Verfasst von), Andrei Stomakhin (Verfasst von), Anastasia Zenchenko (Verfasst von), Vladimir Oslovsky (Verfasst von), Mikhail Drenichev (Verfasst von), Vladimir Prassolov (Verfasst von), Pavel Spirin (Verfasst von)
• Format: Buch
• Veröffentlicht: MDPI AG, 2023-09-01T00:00:00Z.
• Schlagworte: article
• Online-Zugang: Connect to this object online.

Nucleoside reverse transcriptase inhibitors are the first class of drugs to be approved by the FDA for the suppression of HIV-1 and are widely used for this purpose in combination with drugs of other classes. Despite the progress in HIV-1 treatment, there is still the need to develop novel efficient...