The adaptor protein PID1 regulates receptor-dependent endocytosis of postprandial triglyceride-rich lipoproteins

• Главные авторы: Alexander W. Fischer (Автор), Kirstin Albers (Автор), Lucia M. Krott (Автор), Britta Hoffzimmer (Автор), Markus Heine (Автор), Hartwig Schmale (Автор), Ludger Scheja (Автор), Philip L.S.M. Gordts (Автор), Joerg Heeren (Автор)
• Формат: ‌
• Опубликовано: Elsevier, 2018-10-01T00:00:00Z.
• Предметы: article
• Online-ссылка: Connect to this object online.

Objective: Insulin resistance is associated with impaired receptor dependent hepatic uptake of triglyceride-rich lipoproteins (TRL), promoting hypertriglyceridemia and atherosclerosis. Next to low-density lipoprotein (LDL) receptor (LDLR) and syndecan-1, the LDLR-related protein 1 (LRP1) stimulated...