A simplified two-marker immunohistochemistry strategy for Lynch syndrome screening in endometrial cancer patients

• Главные авторы: Ala Aiob (Автор), Yeo Rae Kim (Автор), Kidong Kim (Автор), Hyojin Kim (Автор), Yong Beom Kim (Автор), Duck Woo Kim (Автор), Jae Hong No (Автор), Soo Hyun Seo (Автор), Dong Hoon Suh (Автор), Kyoung Un Park (Автор)
• Формат: ‌
• Опубликовано: Korean Society of Obstetrics and Gynecology, 2023-11-01T00:00:00Z.
• Предметы: article
• Online-ссылка: Connect to this object online.

Objective To examine the efficacy of MSH6 and PMS2 immunohistochemistry (IHC) as a screening method for Lynch syndrome in endometrial cancer patients. Methods Through multidisciplinary discussions, an institutional MSH6 and PMS2 IHC-initiated cascade test (MSH6, PMS2 IHC→microsatellite instability [...