A simplified two-marker immunohistochemistry strategy for Lynch syndrome screening in endometrial cancer patients

• मुख्य लेखकों: Ala Aiob (लेखक), Yeo Rae Kim (लेखक), Kidong Kim (लेखक), Hyojin Kim (लेखक), Yong Beom Kim (लेखक), Duck Woo Kim (लेखक), Jae Hong No (लेखक), Soo Hyun Seo (लेखक), Dong Hoon Suh (लेखक), Kyoung Un Park (लेखक)
• स्वरूप: पुस्तक
• प्रकाशित: Korean Society of Obstetrics and Gynecology, 2023-11-01T00:00:00Z.
• विषय: article
• ऑनलाइन पहुंच: Connect to this object online.

Objective To examine the efficacy of MSH6 and PMS2 immunohistochemistry (IHC) as a screening method for Lynch syndrome in endometrial cancer patients. Methods Through multidisciplinary discussions, an institutional MSH6 and PMS2 IHC-initiated cascade test (MSH6, PMS2 IHC→microsatellite instability [...