Identification and characterization of the Cucurbitacins, a novel class of small-molecule inhibitors of Tropomyosin receptor kinase a
Abstract Background NGF-TrkA is well known to play a key role in propagating and sustaining pruritogenic signals, which form the pathology of chronic pruritus. Inhibition of NGF-TrkA is a known strategy for the treatment of pruritus. In the present paper, we describe the identification, in vitro cha...
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Main Authors: | , , , , , , , , , |
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Formato: | Livro |
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BMC,
2019-11-01T00:00:00Z.
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A1234.567 |
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