HMGB1 and Extracellular Histones Significantly Contribute to Systemic Inflammation and Multiple Organ Failure in Acute Liver Failure

• Asıl Yazarlar: Runkuan Yang (Yazar), Xiaoping Zou (Yazar), Jyrki Tenhunen (Yazar), Tor Inge Tønnessen (Yazar)
• Materyal Türü: Kitap
• Baskı/Yayın Bilgisi: Hindawi Limited, 2017-01-01T00:00:00Z.
• Konular: article
• Online Erişim: Connect to this object online.

Acute liver failure (ALF) is the culmination of severe liver cell injury from a variety of causes. ALF occurs when the extent of hepatocyte death exceeds the hepatic regenerative capacity. ALF has a high mortality that is associated with multiple organ failure (MOF) and sepsis; however, the underlyi...