Antisense transcription from lentiviral gene targeting linked to an integrated stress response in colorectal cancer cells

• Κύριοι συγγραφείς: Taekyu Ha (Συγγραφέας), Michael DiPrima (Συγγραφέας), Vishal Koparde (Συγγραφέας), Parthav Jailwala (Συγγραφέας), Hidetaka Ohnuki (Συγγραφέας), Jing-Xin Feng (Συγγραφέας), Murali Palangat (Συγγραφέας), Daniel Larson (Συγγραφέας), Giovanna Tosato (Συγγραφέας)
• Μορφή: Βιβλίο
• Έκδοση: Elsevier, 2022-06-01T00:00:00Z.
• Θέματα: article
• Διαθέσιμο Online: Connect to this object online.

Advances in gene therapy research have resulted in the successful development of new therapies for clinical use. Here, we explored a gene targeting approach to deplete ephrinB2 from colorectal cancer cells using an inducible lentiviral vector. EphrinB2, a transmembrane ephrin ligand, promotes colore...