Ibuprofen nanocrystals developed by 22 factorial design experiment: A new approach for poorly water-soluble drugs

• Asıl Yazarlar: A.R. Fernandes (Yazar), N.R. Ferreira (Yazar), J.F. Fangueiro (Yazar), A.C. Santos (Yazar), F.J. Veiga (Yazar), C. Cabral (Yazar), A.M. Silva (Yazar), E.B. Souto (Yazar)
• Materyal Türü: Kitap
• Baskı/Yayın Bilgisi: Elsevier, 2017-12-01T00:00:00Z.
• Konular: article
• Online Erişim: Connect to this object online.

The reduction of the particle size of drugs of pharmaceutical interest down to the nano-sized range has dramatically changed their physicochemical properties. The greatest disadvantage of nanocrystals is their inherent instability, due to the risk of crystal growth. Thus, the selection of an appropr...