Halothane Sensitizes the Guinea-Pig Heart to Pharmacological IKr Blockade: Comparison With Urethane Anesthesia
Potential utility of halothane-anesthetized guinea pigs for detecting drug-induced repolarization delay was analyzed in comparison with urethane-anesthesia (n = 4 for both groups). Basal QT interval was significantly greater under halothane-anesthesia than urethane-anesthesia (192 ± 7 vs 132 ± 5 ms,...
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| Main Authors: | , , , , , |
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| Format: | Book |
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Elsevier,
2005-01-01T00:00:00Z.
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