Functional assays to determine the significance of two common <it>XPC </it>3'UTR variants found in bladder cancer patients

• Autors principals: Bishop D (Autor), Hall Janet (Autor), Bentley Johanne (Autor), Vaslin Laurence (Autor), Elliott Faye (Autor), Scott Gina B (Autor), Qiao Boling (Autor), Knowles Margaret A (Autor), Kiltie Anne E (Autor)
• Format: Llibre
• Publicat: BMC, 2011-06-01T00:00:00Z.
• Matèries: article
• Accés en línia: Connect to this object online.

<p>Abstract</p> <p>Background</p> <p><it>XPC </it>is involved in the nucleotide excision repair of DNA damaged by carcinogens known to cause bladder cancer. Individuals homozygous for the variant allele of <it>XPC </it>c.1496C > T (p.Ala499Val...