Loss of carnitine palmitoyltransferase 1a reduces docosahexaenoic acid-containing phospholipids and drives sexually dimorphic liver disease in mice

• मुख्य लेखकों: Mikala M. Zelows (लेखक), Corissa Cady (लेखक), Nikitha Dharanipragada (लेखक), Anna E. Mead (लेखक), Zachary A. Kipp (लेखक), Evelyn A. Bates (लेखक), Venkateshwari Varadharajan (लेखक), Rakhee Banerjee (लेखक), Se-Hyung Park (लेखक), Nathan R. Shelman (लेखक), Harrison A. Clarke (लेखक), Tara R. Hawkinson (लेखक), Terrymar Medina (लेखक), Ramon C. Sun (लेखक), Todd A. Lydic (लेखक), Terry D. Hinds, Jr (लेखक), J. Mark Brown (लेखक), Samir Softic (लेखक), Gregory A. Graf (लेखक), Robert N. Helsley (लेखक)
• स्वरूप: पुस्तक
• प्रकाशित: Elsevier, 2023-12-01T00:00:00Z.
• विषय: article
• ऑनलाइन पहुंच: Connect to this object online.

Background and aims: Genome and epigenome wide association studies identified variants in carnitine palmitoyltransferase 1a (CPT1a) that associate with lipid traits. The goal of this study was to determine the role of liver-specific CPT1a on hepatic lipid metabolism. Approach and results: Male and f...