Dimethyl Fumarate and Its Esters: A Drug with Broad Clinical Utility?

• Main Authors: Stephanie Kourakis (Author), Cara A. Timpani (Author), Judy B. de Haan (Author), Nuri Gueven (Author), Dirk Fischer (Author), Emma Rybalka (Author)
• Format: Book
• Published: MDPI AG, 2020-10-01T00:00:00Z.
• Subjects: article
• Online Access: Connect to this object online.

Fumaric acid esters (FAEs) are small molecules with anti-oxidative, anti-inflammatory and immune-modulating effects. Dimethyl fumarate (DMF) is the best characterised FAE and is approved and registered for the treatment of psoriasis and Relapsing-Remitting Multiple Sclerosis (RRMS). Psoriasis and RR...