Dimethyl Fumarate and Its Esters: A Drug with Broad Clinical Utility?

• Egile Nagusiak: Stephanie Kourakis (Egilea), Cara A. Timpani (Egilea), Judy B. de Haan (Egilea), Nuri Gueven (Egilea), Dirk Fischer (Egilea), Emma Rybalka (Egilea)
• Formatua: Liburua
• Argitaratua: MDPI AG, 2020-10-01T00:00:00Z.
• Gaiak: article
• Sarrera elektronikoa: Connect to this object online.

Fumaric acid esters (FAEs) are small molecules with anti-oxidative, anti-inflammatory and immune-modulating effects. Dimethyl fumarate (DMF) is the best characterised FAE and is approved and registered for the treatment of psoriasis and Relapsing-Remitting Multiple Sclerosis (RRMS). Psoriasis and RR...