The Effect of Serine Protease Inhibitors on Visceral Pain in Different Rodent Models With an Intestinal Insult

• Váldodahkkit: Hannah Ceuleers (Dahkki), Nikita Hanning (Dahkki), Michelle De bruyn (Dahkki), Joris G De Man (Dahkki), Heiko U De Schepper (Dahkki), Qian Li (Dahkki), Liansheng Liu (Dahkki), Steven Abrams (Dahkki), Annemieke Smet (Dahkki), Jurgen Joossens (Dahkki), Koen Augustyns (Dahkki), Ingrid De Meester (Dahkki), Pankaj J Pasricha (Dahkki), Benedicte Y De Winter (Dahkki)
• Materiálatiipa: Girji
• Almmustuhtton: Frontiers Media S.A., 2022-06-01T00:00:00Z.
• Fáttát: article
• Liŋkkat: Connect to this object online.

Background: Serine proteases are believed to play a key role in the origin of abdominal pain in IBD and IBS. We previously demonstrated a reduction of visceral pain in a post-inflammatory IBS rat model after a single intraperitoneal or intracolonic administration of a serine protease inhibitor. The...