The Effect of Serine Protease Inhibitors on Visceral Pain in Different Rodent Models With an Intestinal Insult

• Автори: Hannah Ceuleers (Автор), Nikita Hanning (Автор), Michelle De bruyn (Автор), Joris G De Man (Автор), Heiko U De Schepper (Автор), Qian Li (Автор), Liansheng Liu (Автор), Steven Abrams (Автор), Annemieke Smet (Автор), Jurgen Joossens (Автор), Koen Augustyns (Автор), Ingrid De Meester (Автор), Pankaj J Pasricha (Автор), Benedicte Y De Winter (Автор)
• Формат: Книга
• Опубліковано: Frontiers Media S.A., 2022-06-01T00:00:00Z.
• Предмети: article
• Онлайн доступ: Connect to this object online.

Background: Serine proteases are believed to play a key role in the origin of abdominal pain in IBD and IBS. We previously demonstrated a reduction of visceral pain in a post-inflammatory IBS rat model after a single intraperitoneal or intracolonic administration of a serine protease inhibitor. The...