Exploring the Leukemogenic Potential of GATA-1_S, the Shorter Isoform of GATA-1: Novel Insights into Mechanisms Hampering Respiratory Chain Complex II Activity and Limiting Oxidative Phosphorylation Efficiency

• Asıl Yazarlar: Silvia Trombetti (Yazar), Raffaele Sessa (Yazar), Rosa Catapano (Yazar), Laura Rinaldi (Yazar), Alessandra Lo Bianco (Yazar), Antonio Feliciello (Yazar), Paola Izzo (Yazar), Michela Grosso (Yazar)
• Materyal Türü: Kitap
• Baskı/Yayın Bilgisi: MDPI AG, 2021-10-01T00:00:00Z.
• Konular: article
• Online Erişim: Connect to this object online.

GATA-1 is a key regulator of hematopoiesis. A balanced ratio of its two isoforms, GATA-1_FL and GATA-1_S, contributes to normal hematopoiesis, whereas aberrant expression of GATA-1_S alters the differentiation/proliferation potential...