Quantitative global and gene-specific promoter methylation in relation to biological properties of neuroblastomas

• Main Authors: Kiss Nimrod B (Author), Kogner Per (Author), Johnsen John (Author), Martinsson Tommy (Author), Larsson Catharina (Author), Geli Janos (Author)
• Format: Book
• Published: BMC, 2012-09-01T00:00:00Z.
• Subjects: article
• Online Access: Connect to this object online.

<p>Abstract</p> <p>Background</p> <p>In this study we aimed to quantify tumor suppressor gene (TSG) promoter methylation densities levels in primary neuroblastoma tumors and cell lines. A subset of these TSGs is associated with a CpG island methylator phenotype (CIMP) i...