Quantitative global and gene-specific promoter methylation in relation to biological properties of neuroblastomas

• Auteurs principaux: Kiss Nimrod B (Auteur), Kogner Per (Auteur), Johnsen John (Auteur), Martinsson Tommy (Auteur), Larsson Catharina (Auteur), Geli Janos (Auteur)
• Format: Livre
• Publié: BMC, 2012-09-01T00:00:00Z.
• Sujets: article
• Accès en ligne: Connect to this object online.

<p>Abstract</p> <p>Background</p> <p>In this study we aimed to quantify tumor suppressor gene (TSG) promoter methylation densities levels in primary neuroblastoma tumors and cell lines. A subset of these TSGs is associated with a CpG island methylator phenotype (CIMP) i...