Porphyromonas gingivalis bacteremia increases the permeability of the blood-brain barrier via the Mfsd2a/Caveolin-1 mediated transcytosis pathway

• Главные авторы: Shuang Lei (Автор), Jian Li (Автор), Jingjun Yu (Автор), Fulong Li (Автор), Yaping Pan (Автор), Xu Chen (Автор), Chunliang Ma (Автор), Weidong Zhao (Автор), Xiaolin Tang (Автор)
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• Опубликовано: Nature Publishing Group, 2023-01-01T00:00:00Z.
• Предметы: article
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Abstract Bacteremia induced by periodontal infection is an important factor for periodontitis to threaten general health. P. gingivalis DNA/virulence factors have been found in the brain tissues from patients with Alzheimer's disease (AD). The blood-brain barrier (BBB) is essential for keeping...