Potential of mucoadhesive chitosan glutamate microparticles as microbicide carriers - antiherpes activity and penetration behavior across the human vaginal epithelium

• المؤلفون الرئيسيون: Emilia Szymańska (مؤلف), Małgorzata Krzyżowska (مؤلف), Krzysztof Cal (مؤلف), Barbara Mikolaszek (مؤلف), Jakub Tomaszewski (مؤلف), Sławomir Wołczyński (مؤلف), Katarzyna Winnicka (مؤلف)
• التنسيق: كتاب
• منشور في: Taylor & Francis Group, 2021-01-01T00:00:00Z.
• الموضوعات: article
• الوصول للمادة أونلاين: Connect to this object online.

Chitosan glutamate (gCS) spray-dried microparticles appear promising carriers to overcome challenges associated with vaginal microbicide delivery. This study aimed at elucidating the penetration and mucoadhesive behavior of developed gCS multiunit carriers with zidovudine (ZVD) as a model antiretrov...