NLRP3 controls Trypanosoma cruzi infection through a caspase-1-dependent IL-1R-independent NO production.

• Główni autorzy: Virginia M Gonçalves (Autor), Kely C Matteucci (Autor), Carina L Buzzo (Autor), Bruna H Miollo (Autor), Danny Ferrante (Autor), Ana C Torrecilhas (Autor), Mauricio M Rodrigues (Autor), Jose M Alvarez (Autor), Karina R Bortoluci (Autor)
• Format: Książka
• Wydane: Public Library of Science (PLoS), 2013-01-01T00:00:00Z.
• Hasła przedmiotowe: article
• Dostęp online: Connect to this object online.

Trypanosoma cruzi (T. cruzi) is an intracellular protozoan parasite and the etiological agent of Chagas disease, a chronic infectious illness that affects millions of people worldwide. Although the role of TLR and Nod1 in the control of T. cruzi infection is well-established, the involvement of infl...