Arecoline suppresses epithelial cell viability by upregulating tropomyosin-1 through the transforming growth factor-β/Smad pathway

• Κύριοι συγγραφείς: Long Li (Συγγραφέας), Liqun Gu (Συγγραφέας), Zhigang Yao (Συγγραφέας), Yuehong Wang (Συγγραφέας), Zhangui Tang (Συγγραφέας), Xiaoying Wu (Συγγραφέας)
• Μορφή: Βιβλίο
• Έκδοση: Taylor & Francis Group, 2020-01-01T00:00:00Z.
• Θέματα: article
• Διαθέσιμο Online: Connect to this object online.

Context Oral submucous fibrosis (OSF) is a chronic and progressive disease. Arecoline, present in betel nuts, has been proposed as a vital aetiological factor. However, the underlying mechanism remains unclear. Objectives This research elucidates the expression of tropomyosin-1 (TPM1) and its regula...