Modulation of sleep behavior in zebrafish larvae by pharmacological targeting of the orexin receptor

• मुख्य लेखकों: Marie Pardon (लेखक), Pieter Claes (लेखक), Sarah Druwé (लेखक), Murielle Martini (लेखक), Aleksandra Siekierska (लेखक), Christel Menet (लेखक), Peter A. M. de Witte (लेखक), Daniëlle Copmans (लेखक)
• स्वरूप: पुस्तक
• प्रकाशित: Frontiers Media S.A., 2022-10-01T00:00:00Z.
• विषय: article
• ऑनलाइन पहुंच: Connect to this object online.

New pharmacological approaches that target orexin receptors (OXRs) are being developed to treat sleep disorders such as insomnia and narcolepsy, with fewer side effects than existing treatments. Orexins are neuropeptides that exert excitatory effects on postsynaptic neurons via the OXRs, and are imp...