The effect of 'cytochrome P-450 2C9' and 'vitamin K epoxide reductase complex 1' genetic polymorphism upon oral anticoagulation requirements
Background Polymorphisms in the gene encoding the cytochrome P-450 2C9 enzyme (CYP2C9) are known to contribute to variability in sensitivity to Marevan. CYP2C9 is the enzyme primarily responsible for the metabolic clearance of s-enantiomer of Marevan. The vitamin K epoxide reductase complex 1 (VKORC...
Saved in:
Main Authors: | Hossam Y.K Mohammed (Author), Yousry Z Al-Zohairy (Author), Mahmoud Abd El-Latif Hashish (Author) |
---|---|
Format: | Book |
Published: |
Wolters Kluwer Medknow Publications,
2018-01-01T00:00:00Z.
|
Subjects: | |
Online Access: | Connect to this object online. |
Tags: |
Add Tag
No Tags, Be the first to tag this record!
|
Similar Items
-
Warfarin dose requirement and cytochrome P450 2C9 and Vitamin K epoxide reductase complex subunit 1-1639 genetic polymorphisms in Thai patients
by: Burassakorn Subsuphan, et al.
Published: (2016) -
New insights into the role of cytochrome P450 reductase (POR) in microsomal redox biology
by: Todd D. Porter
Published: (2012) -
Effects of Diminished NADPH:cytochrome P450 Reductase in Human Hepatocytes on Lipid and Bile Acid Homeostasis
by: Tamara Heintze, et al.
Published: (2021) -
The Hinge Segment of Human NADPH-Cytochrome P450 Reductase in Conformational Switching: The Critical Role of Ionic Strength
by: Diana Campelo, et al.
Published: (2017) -
Effects of Cytochrome P450 and Transporter Polymorphisms on the Bioavailability and Safety of Dutasteride and Tamsulosin
by: Gonzalo Villapalos-García, et al.
Published: (2021)