SARS-CoV-2 Switches 'on' MAPK and NFκB Signaling via the Reduction of Nuclear DUSP1 and DUSP5 Expression

• Главные авторы: Swati Goel (Автор), Fatemeh Saheb Sharif-Askari (Автор), Narjes Saheb Sharif Askari (Автор), Bushra Madkhana (Автор), Ahmad Munzer Alwaa (Автор), Bassam Mahboub (Автор), Adel M Zakeri (Автор), Elaref Ratemi (Автор), Rifat Hamoudi (Автор), Qutayba Hamid (Автор), Rabih Halwani (Автор)
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• Опубликовано: Frontiers Media S.A., 2021-04-01T00:00:00Z.
• Предметы: article
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Mitogen-activated protein kinases (MAPK) and NF-kappaB (NF-κB) pathway regulate many cellular processes and are essential for immune cells function. Their activity is controlled by dual-specificity phosphatases (DUSPs). A comprehensive analysis of publicly available gene expression data sets of huma...