Anti-inflammatory effect of a selective 11β-hydroxysteroid dehydrogenase type 1 inhibitor via the stimulation of heme oxygenase-1 in LPS-activated mice and J774.1 murine macrophages

• المؤلفون الرئيسيون: Sung Bum Park (مؤلف), Ji Seon Park (مؤلف), Won Hoon Jung (مؤلف), Hee Youn Kim (مؤلف), Hyun Jung Kwak (مؤلف), Jin Hee Ahn (مؤلف), Kyoung-Jin Choi (مؤلف), Yoon-Ju Na (مؤلف), Sunhwa Choi (مؤلف), Sang Dal Rhee (مؤلف), Ki Young Kim (مؤلف)
• التنسيق: كتاب
• منشور في: Elsevier, 2016-08-01T00:00:00Z.
• الموضوعات: article
• الوصول للمادة أونلاين: Connect to this object online.

11β-Hydroxysteroid dehydrogenase type 1 (11β-HSD1) converts inactive cortisone to the active cortisol. 11β-HSD1 may be involved in the resolution of inflammation. In the present study, we investigate the anti-inflammatory effects of 2-(3-benzoyl)-4-hydroxy-1,1-dioxo-2H-1,2-benzothiazine-2-yl-1-pheny...