The extrahepatic role of TFR2 in iron homeostasis

• Asıl Yazarlar: Laura eSilvestri (Yazar), Antonella eNai (Yazar), Alessia ePagani (Yazar), Clara eCamaschella (Yazar)
• Materyal Türü: Kitap
• Baskı/Yayın Bilgisi: Frontiers Media S.A., 2014-05-01T00:00:00Z.
• Konular: article
• Online Erişim: Connect to this object online.

Transferrin receptor 2 (TFR2), a protein homologous to the cell iron importer transferrin receptor 1 (TFR1), is expressed in the liver and erythroid cells and is reported to bind diferric transferrin, although at lower affinity than TFR1. TFR2 gene is mutated in type 3 hemochromatosis, a disorder ch...