Nanog interaction with the androgen receptor signaling axis induce ovarian cancer stem cell regulation: studies based on the CRISPR/Cas9 system

• Hauptverfasser: Kaijian Ling (Verfasst von), Lupin Jiang (Verfasst von), Shi Liang (Verfasst von), Joseph Kwong (Verfasst von), Leiyan Yang (Verfasst von), Yudi Li (Verfasst von), PingYin (Verfasst von), Qingchun Deng (Verfasst von), Zhiqing Liang (Verfasst von)
• Format: Buch
• Veröffentlicht: BMC, 2018-05-01T00:00:00Z.
• Schlagworte: article
• Online-Zugang: Connect to this object online.

Abstract Background Ovarian cancer stem cells (OCSCs) contribute to the poor prognosis of ovarian cancer. Involvement of the androgen receptor (AR) in the malignant behaviors of other tumors has been reported. However, whether AR associates with Nanog (a stem cell marker) and participates in OCSC fu...