Nicotinamide riboside kinases display redundancy in mediating nicotinamide mononucleotide and nicotinamide riboside metabolism in skeletal muscle cells

• मुख्य लेखकों: Rachel S. Fletcher (लेखक), Joanna Ratajczak (लेखक), Craig L. Doig (लेखक), Lucy A. Oakey (लेखक), Rebecca Callingham (लेखक), Gabriella Da Silva Xavier (लेखक), Antje Garten (लेखक), Yasir S. Elhassan (लेखक), Philip Redpath (लेखक), Marie E. Migaud (लेखक), Andrew Philp (लेखक), Charles Brenner (लेखक), Carles Canto (लेखक), Gareth G. Lavery (लेखक)
• स्वरूप: पुस्तक
• प्रकाशित: Elsevier, 2017-08-01T00:00:00Z.
• विषय: article
• ऑनलाइन पहुंच: Connect to this object online.

Objective: Augmenting nicotinamide adenine dinucleotide (NAD+) availability may protect skeletal muscle from age-related metabolic decline. Dietary supplementation of NAD+ precursors nicotinamide mononucleotide (NMN) and nicotinamide riboside (NR) appear efficacious in elevating muscle NAD+. Here we...