Nicotinamide riboside kinases display redundancy in mediating nicotinamide mononucleotide and nicotinamide riboside metabolism in skeletal muscle cells

• Główni autorzy: Rachel S. Fletcher (Autor), Joanna Ratajczak (Autor), Craig L. Doig (Autor), Lucy A. Oakey (Autor), Rebecca Callingham (Autor), Gabriella Da Silva Xavier (Autor), Antje Garten (Autor), Yasir S. Elhassan (Autor), Philip Redpath (Autor), Marie E. Migaud (Autor), Andrew Philp (Autor), Charles Brenner (Autor), Carles Canto (Autor), Gareth G. Lavery (Autor)
• Format: Książka
• Wydane: Elsevier, 2017-08-01T00:00:00Z.
• Hasła przedmiotowe: article
• Dostęp online: Connect to this object online.

Objective: Augmenting nicotinamide adenine dinucleotide (NAD+) availability may protect skeletal muscle from age-related metabolic decline. Dietary supplementation of NAD+ precursors nicotinamide mononucleotide (NMN) and nicotinamide riboside (NR) appear efficacious in elevating muscle NAD+. Here we...