Predicting capsule fill weight from in-situ powder density measurements using terahertz reflection technology

• Autors principals: Sandra Stranzinger (Autor), Eva Faulhammer (Autor), Jingyi Li (Autor), Runqiao Dong (Autor), J. Axel Zeitler (Autor), Stefano Biserni (Autor), Vittorio Calzolari (Autor), Johannes G. Khinast (Autor), Daniel Markl (Autor)
• Format: Llibre
• Publicat: Elsevier, 2019-12-01T00:00:00Z.
• Matèries: article
• Accés en línia: Connect to this object online.

The manufacturing of the majority of solid oral dosage forms is based on the densification of powder. A good understanding of the powder behavior is therefore essential to assure high quality drug products. This is particularly relevant for the capsule filling process, where the powder bulk density...