In vitro evaluation of sustained released matrix tablets containing ibuprofen: a model poorly water-soluble drug

• मुख्य लेखकों: Wendy Leticia Guerra-Ponce (लेखक), Sandra Leticia Gracia-Vásquez (लेखक), Patricia González-Barranco (लेखक), Ivonne Antonieta Camacho-Mora (लेखक), Yolanda Araceli Gracia-Vásquez (लेखक), Elizabeth Orozco-Beltrán (लेखक), Linda Anne Felton (लेखक)
• स्वरूप: पुस्तक
• प्रकाशित: Universidade de São Paulo.
• विषय: article
• ऑनलाइन पहुंच: Connect to this object online.

ABSTRACT A matrix system was developed that releases ibuprofen (IB) over a 12-hour period and the influence of the polymer type and concentration on the release rate of the drug was evaluated. Tablets containing different concentrations of Carbopol (CP), hydroxypropyl methylcellulose (HPMC), or ethy...