In vitro evaluation of sustained released matrix tablets containing ibuprofen: a model poorly water-soluble drug

• Những tác giả chính: Wendy Leticia Guerra-Ponce (Tác giả), Sandra Leticia Gracia-Vásquez (Tác giả), Patricia González-Barranco (Tác giả), Ivonne Antonieta Camacho-Mora (Tác giả), Yolanda Araceli Gracia-Vásquez (Tác giả), Elizabeth Orozco-Beltrán (Tác giả), Linda Anne Felton (Tác giả)
• Định dạng: Sách
• Được phát hành: Universidade de São Paulo.
• Những chủ đề: article
• Truy cập trực tuyến: Connect to this object online.

ABSTRACT A matrix system was developed that releases ibuprofen (IB) over a 12-hour period and the influence of the polymer type and concentration on the release rate of the drug was evaluated. Tablets containing different concentrations of Carbopol (CP), hydroxypropyl methylcellulose (HPMC), or ethy...