CCR9 overexpression promotes T-ALL progression by enhancing cholesterol biosynthesis

• Egile Nagusiak: Muhammad Jamal (Egilea), Yufei Lei (Egilea), Hengjing He (Egilea), Xingruo Zeng (Egilea), Hina Iqbal Bangash (Egilea), Di Xiao (Egilea), Liang Shao (Egilea), Fuling Zhou (Egilea), Quiping Zhang (Egilea)
• Formatua: Liburua
• Argitaratua: Frontiers Media S.A., 2023-09-01T00:00:00Z.
• Gaiak: article
• Sarrera elektronikoa: Connect to this object online.

Introduction: T-cell acute lymphoblastic leukemia (T-ALL) is an aggressive hematological malignancy of the lymphoid progenitor cells, contributing to ∼ 20% of the total ALL cases, with a higher prevalence in adults than children. Despite the important role of human T-ALL cell lines in understanding...