CCR9 overexpression promotes T-ALL progression by enhancing cholesterol biosynthesis

• Main Authors: Muhammad Jamal (Author), Yufei Lei (Author), Hengjing He (Author), Xingruo Zeng (Author), Hina Iqbal Bangash (Author), Di Xiao (Author), Liang Shao (Author), Fuling Zhou (Author), Quiping Zhang (Author)
• Format: Book
• Published: Frontiers Media S.A., 2023-09-01T00:00:00Z.
• Subjects: article
• Online Access: Connect to this object online.

Introduction: T-cell acute lymphoblastic leukemia (T-ALL) is an aggressive hematological malignancy of the lymphoid progenitor cells, contributing to ∼ 20% of the total ALL cases, with a higher prevalence in adults than children. Despite the important role of human T-ALL cell lines in understanding...