The Role of Sirtuin 3 in Radiation-Induced Long-Term Persistent Liver Injury

• Главные авторы: Francesca V. LoBianco (Автор), Kimberly J. Krager (Автор), Gwendolyn S. Carter (Автор), Sinthia Alam (Автор), Youzhong Yuan (Автор), Elise G. Lavoie (Автор), Jonathan A. Dranoff (Автор), Nukhet Aykin-Burns (Автор)
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• Опубликовано: MDPI AG, 2020-05-01T00:00:00Z.
• Предметы: article
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In patients with abdominal region cancers, ionizing radiation (IR)-induced long-term liver injury is a major limiting factor in the use of radiotherapy. Previously, the major mitochondrial deacetylase, sirtuin 3 (SIRT3), has been implicated to play an important role in the development of acute liver...