Targeted suicide gene therapy for liver cancer based on ribozyme-mediated RNA replacement through post-transcriptional regulation
Hepatocellular carcinoma (HCC) has high fatality rate and limited therapeutic options. Here, we propose a new anti-HCC approach with high cancer-selectivity and efficient anticancer effects, based on adenovirus-mediated Tetrahymena group I trans-splicing ribozymes specifically inducing targeted suic...
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| Main Authors: | , , , , , , , , , , , , |
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| Format: | Book |
| Published: |
Elsevier,
2021-03-01T00:00:00Z.
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| Subjects: | |
| Online Access: | Connect to this object online. |
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