Proof-of-Principle Study of Inflammasome Signaling Proteins as Diagnostic Biomarkers of the Inflammatory Response in Parkinson's Disease

• Main Authors: Erika d. l. R. M. Cabrera Ranaldi (Author), Karen Nuytemans (Author), Anisley Martinez (Author), Corneliu C. Luca (Author), Robert W. Keane (Author), Juan Pablo de Rivero Vaccari (Author)
• Format: Book
• Published: MDPI AG, 2023-06-01T00:00:00Z.
• Subjects: article
• Online Access: Connect to this object online.

Parkinson's disease (PD) is a neurodegenerative disorder marked by the death of dopaminergic neurons in the midbrain, the accumulation of α-synuclein aggregates, and motor deficits. A major contributor to dopaminergic neuronal loss is neuroinflammation. The inflammasome is a multiprotein comple...