Proof-of-Principle Study of Inflammasome Signaling Proteins as Diagnostic Biomarkers of the Inflammatory Response in Parkinson's Disease

• Hlavní autoři: Erika d. l. R. M. Cabrera Ranaldi (Autor), Karen Nuytemans (Autor), Anisley Martinez (Autor), Corneliu C. Luca (Autor), Robert W. Keane (Autor), Juan Pablo de Rivero Vaccari (Autor)
• Médium: Kniha
• Vydáno: MDPI AG, 2023-06-01T00:00:00Z.
• Témata: article
• On-line přístup: Connect to this object online.

Parkinson's disease (PD) is a neurodegenerative disorder marked by the death of dopaminergic neurons in the midbrain, the accumulation of α-synuclein aggregates, and motor deficits. A major contributor to dopaminergic neuronal loss is neuroinflammation. The inflammasome is a multiprotein comple...