Eph A10-modified pH-sensitive liposomes loaded with novel triphenylphosphine-docetaxel conjugate possess hierarchical targetability and sufficient antitumor effect both in vitro and in vivo

• Egile Nagusiak: Jiulong Zhang (Egilea), Chunrong Yang (Egilea), Shuang Pan (Egilea), Menghao Shi (Egilea), Jie Li (Egilea), Haiyang Hu (Egilea), Mingxi Qiao (Egilea), Dawei Chen (Egilea), Xiuli Zhao (Egilea)
• Formatua: Liburua
• Argitaratua: Taylor & Francis Group, 2018-01-01T00:00:00Z.
• Gaiak: article
• Sarrera elektronikoa: Connect to this object online.

Mitochondrial-targeting therapy was considered to be a promising approach for the efficient treatment of cancer while positive charge induced nonspecific cytotoxicity severely limits its application. To overcome this drawback, a novel mitochondria targeted conjugate triphenylphosphine-docetaxel (TD)...