Eph A10-modified pH-sensitive liposomes loaded with novel triphenylphosphine-docetaxel conjugate possess hierarchical targetability and sufficient antitumor effect both in vitro and in vivo

• Päätekijät: Jiulong Zhang (Tekijä), Chunrong Yang (Tekijä), Shuang Pan (Tekijä), Menghao Shi (Tekijä), Jie Li (Tekijä), Haiyang Hu (Tekijä), Mingxi Qiao (Tekijä), Dawei Chen (Tekijä), Xiuli Zhao (Tekijä)
• Aineistotyyppi: Kirja
• Julkaistu: Taylor & Francis Group, 2018-01-01T00:00:00Z.
• Aiheet: article
• Linkit: Connect to this object online.

Mitochondrial-targeting therapy was considered to be a promising approach for the efficient treatment of cancer while positive charge induced nonspecific cytotoxicity severely limits its application. To overcome this drawback, a novel mitochondria targeted conjugate triphenylphosphine-docetaxel (TD)...