Developmental Changes in Excitation-Contraction Mechanisms of the Mouse Ventricular Myocardium as Revealed by Functional and Confocal Imaging Analyses

• Auteurs principaux: Shogo Hamaguchi (Auteur), Yuko Kawakami (Auteur), Yoriko Honda (Auteur), Kana Nemoto (Auteur), Ayaka Sano (Auteur), Iyuki Namekata (Auteur), Hikaru Tanaka (Auteur)
• Format: Livre
• Publié: Elsevier, 2013-01-01T00:00:00Z.
• Sujets: article
• Accès en ligne: Connect to this object online.

Developmental changes in excitation-contraction mechanisms were examined in the ventricular myocardium from fetal, neonatal, and 1-, 2-, and 4-week-old mice. In isolated tissue, the negative inotropic effect of nifedipine decreased, while that of ryanodine increased with age. Action potential durati...