Assessing the activity of nonsense-mediated mRNA decay in lung cancer

Abstract Background Inhibition of nonsense-mediated mRNA decay (NMD) in tumor cells can suppress tumor growth through expressing new antigens whose mRNAs otherwise are degraded by NMD. Thus NMD inhibition is a promising approach for developing cancer therapies. Apparently, the success of this approa...

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Autores principales: Meng Wang (Autor), Peiwei Zhang (Autor), Yufei Zhu (Autor), Xiangyin Kong (Autor), Zhenguo Zhang (Autor), Landian Hu (Autor)
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Publicado: BMC, 2017-09-01T00:00:00Z.
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