Assessing the activity of nonsense-mediated mRNA decay in lung cancer

Abstract Background Inhibition of nonsense-mediated mRNA decay (NMD) in tumor cells can suppress tumor growth through expressing new antigens whose mRNAs otherwise are degraded by NMD. Thus NMD inhibition is a promising approach for developing cancer therapies. Apparently, the success of this approa...

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Main Authors: Meng Wang (Author), Peiwei Zhang (Author), Yufei Zhu (Author), Xiangyin Kong (Author), Zhenguo Zhang (Author), Landian Hu (Author)
Formato: Livro
Publicado em: BMC, 2017-09-01T00:00:00Z.
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