Assessing the activity of nonsense-mediated mRNA decay in lung cancer

• मुख्य लेखकों: Meng Wang (लेखक), Peiwei Zhang (लेखक), Yufei Zhu (लेखक), Xiangyin Kong (लेखक), Zhenguo Zhang (लेखक), Landian Hu (लेखक)
• स्वरूप: पुस्तक
• प्रकाशित: BMC, 2017-09-01T00:00:00Z.
• विषय: article
• ऑनलाइन पहुंच: Connect to this object online.

Abstract Background Inhibition of nonsense-mediated mRNA decay (NMD) in tumor cells can suppress tumor growth through expressing new antigens whose mRNAs otherwise are degraded by NMD. Thus NMD inhibition is a promising approach for developing cancer therapies. Apparently, the success of this approa...