Evaluation of the influence of fluoroquinolone chemical structure on stability: forced degradation and in silico studies

• প্রধান লেখক: André Valle de Bairros (লেখক), Danillo Baptista Pereira (লেখক), Everson Willian Fialho Cordeiro (লেখক), Clésio Soldateli Paim (লেখক), Fabiana Ernestina Barcellos da Silva (লেখক), Marcelo Donadel Malesuik (লেখক), Fávero Reisdorfer Paula (লেখক)
• বিন্যাস: গ্রন্থ
• প্রকাশিত: Universidade de São Paulo, 2018-05-01T00:00:00Z.
• বিষয়গুলি: article
• অনলাইন ব্যবহার করুন: Connect to this object online.

ABSTRACT Fluoroquinolones are a known antibacterial class commonly used around the world. These compounds present relative stability and they may show some adverse effects according their distinct chemical structures. The chemical hydrolysis of five fluoroquinolones was studied using alkaline and ph...