Differential regulation of the unfolded protein response in outbred deer mice and susceptibility to metabolic disease

• Автори: Amanda Havighorst (Автор), Youwen Zhang (Автор), Elena Farmaki (Автор), Vimala Kaza (Автор), Ioulia Chatzistamou (Автор), Hippokratis Kiaris (Автор)
• Формат: Книга
• Опубліковано: The Company of Biologists, 2019-02-01T00:00:00Z.
• Предмети: article
• Онлайн доступ: Connect to this object online.

Endoplasmic reticulum (ER) stress has been causatively linked to the onset of various pathologies. However, whether and how inherent variations in the resulting unfolded protein response (UPR) affect predisposition to ER-stress-associated metabolic conditions remains to be established. By using gene...