Differential regulation of the unfolded protein response in outbred deer mice and susceptibility to metabolic disease

• Những tác giả chính: Amanda Havighorst (Tác giả), Youwen Zhang (Tác giả), Elena Farmaki (Tác giả), Vimala Kaza (Tác giả), Ioulia Chatzistamou (Tác giả), Hippokratis Kiaris (Tác giả)
• Định dạng: Sách
• Được phát hành: The Company of Biologists, 2019-02-01T00:00:00Z.
• Những chủ đề: article
• Truy cập trực tuyến: Connect to this object online.

Endoplasmic reticulum (ER) stress has been causatively linked to the onset of various pathologies. However, whether and how inherent variations in the resulting unfolded protein response (UPR) affect predisposition to ER-stress-associated metabolic conditions remains to be established. By using gene...