Diabetes fuels periodontal lesions via GLUT1-driven macrophage inflammaging

• Hoofdauteurs: Qian Wang (Auteur), Lulingxiao Nie (Auteur), Pengfei Zhao (Auteur), Xinyi Zhou (Auteur), Yi Ding (Auteur), Qianming Chen (Auteur), Qi Wang (Auteur)
• Formaat: Boek
• Gepubliceerd in: Nature Publishing Group, 2021-03-01T00:00:00Z.
• Onderwerpen: article
• Online toegang: Connect to this object online.

Abstract Hyperglycemia induces chronic low-grade inflammation (inflammaging), which is a newly identified contributor to diabetes-related tissue lesions, including the inflammatory bone loss in periodontitis. It is also a secondary senescent pattern mediated by an increased burden of senescent cells...